Advanced Ob/GYN Blog

Who has a high risk of developing breast cancer?

The American Cancer Society recommends that women with a lifetime risk of breast cancer of 20% or greater be screened annually with breast MRI in addition to mammography regardless of breast density. For more information on calculating a woman’s lifetime risk of breast cancer, visit  In addition, genetic counseling can help determine the lifetime risk of breast cancer and thus help a woman decide if additional breast cancer screening is appropriate for her.

Factors that greatly increase the risk of breast cancer include:

  • The BRCA gene mutation
  • A family history of a first-degree relative who has a BRCA gene mutation (for those individuals who have not been tested)
  • Li-Fraumeni, Cowden/PTEN, or Bannayan-Riley-Ruvalcaba syndrome
  • History of chest radiation between the ages of 10 and 30
  • A history of more than one first-degree relative with breast cancer
  • A personal history of invasive breast cancer or ductal carcinoma in situ (DCIS)
  • A personal history of lobular carcinoma in situ (LCIS)or atypical hyperplasia